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The 2022 Thanksgiving Day NFL schedule will conclude when the Minnesota Vikings host the New England Patriots at U.S. Bank Stadium. The Vikings (8-2) will try to bounce back from their worst performance of the season, a 40-3 blowout lo s to Dallas last Sunday. They still lead the NFC North and own the second-best record in the conference. Meanwhile, the Patriots (6-4) are tied for third place in the AFC East, one game behind Buffalo and Miami. They have Rob Windsor Jersey won three in a row and five of their last six.Kickoff is set for 8:20 p.m. ET. Minnesota is a 2.5-point favorite in the latest Vikings vs. Patriots odds from Caesars Sportsbook, while the over/under for total points scored is 42.5. Before you make any Patriots vs. Vikings picks of your own, you need to .White, a Fantasy and gambling editor for CBS Sports, consistently crushes as SportsLine's No. 1 NFL expert in picks against the spread and went 445-378-24 on his ATS picks from 2017-21, which returned $2,542 to $100 players. He's also gone a whopping 52-28-4 (+$2,053) on his last 84 picks involving the Vikings, meaning he's well-qualified for this selection. Anyone who has followed him is way up.Now, he has locked in on Vikings vs. Patriots during the 2022 Thanksgiving NFL schedule and released a confident against-the-spread pick. . Here are the NFL lines and trends for Patriots vs. Vikings: Vikings vs. Patriots spread: Minnesota -2.5Vikings vs. Patriots Over/Under: 42.5 pointsVikings vs. Patriots money line: Minnesota -145, New England +120MIN: WR ranks second in the league in receiving yards (1,093)NE: LB Matthew Judon leads the NFL in sacks (13)Receiver Justin Jefferson continues his record-setting start to his young career. Already a two-time Pro Bowler, Jefferson has 4,109 career receiving yards in just his third season, the third-most in NFL history. He needs just 55 yards by the end of the season to pa s Randy Mo s (4,163) for the most receiving yards through a player's third season in NFL history.In addition, Minnesota faces a New England offense that may be without a key starter. Center and team captain David Andrews is questionable for Thursday with a significant thigh injury he incurred on Sunday against the Jets. His absence would be a setback for a team playing in a loud road environment..The New England pa s rush has a strong matchup against Minnesota's offense. The Patriots rank second in the NFL in sacks (36), behind only the (42). Last week, Vikings quarterback was sacked a career-high seven times by Dallas in a 40-3 lo s. In addition, receiver is having the best season of his young career. The 26-year-old has three receiving touchdowns this season, including two in the past four games, which is more than he had coming into the season (two). He also is averaging a career-high 63.6 receiving yards per game..White has analyzed this matchup and while we can tell you he's leaning Under the total, he has discovered a crucial x-factor that makes one side of the spread a must-back. .Who wins Patriots vs. Vikings as part of the NFL Thanksgiving Day schedule 2022? And what critical factor makes one side of the spread a must-back? .